succinic acid pka

This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance. Degradation rate constant with OH radicals provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. The anion, succinate, is a component of the citric acid or TCA cycle and is capable of donating electrons to the electron transfer chain. In most cases, impurities constitute less than 10% of the substance. This section summarises the partition coefficient values from all registered dossiers for the substance. C&L Inventory . Values are generally displayed in milligram per litre. See ‘Summary effect on fertility oral route’, except: This section displays the values related to neurotoxicity from all registered dossiers for the substance. If so, the data provided is not processed for the Brief Profile. The light blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in CLP notifications. The POPs regulatory processes identified for the Brief Profile are: Classification, Labelling and Packaging (CLP)The CLP Regulation (1272/2008) entered into force on 20 January 2009. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. No or insufficient data available at present, Hazard related to composition of atmosphere identified, No potential to cause toxic effects if accumulated (in higher organisms) via the food chain, bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day), DMEL (Derived Minimum Effect Level) - not included for short–term effects, Insufficient data available (further information necessary), Hazard unknown (no further information necessary), Hazard unknown but no further hazard information necessary as no exposure expected, ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added, Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian), No adverse effect observed (not irritating), Adverse effect observed (irreversible damage), mg/kg bw/day (nominal/actual dose received), See ‘Study results oral: Prioritization by test species’, mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical)), ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received), mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day), mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical)), No study available / no study available (further information necessary). Succinic acid is a diprotic acid. If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre. The Index number for each substance is in the form of a digit sequence of the type ABC-RST-VW-Y. Succinic Acid. Chemical formula: C 4 H 6 O 4. The ‘Scientific properties’ section gives an overview of summarised scientific data from registered dossiers. This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Bacteria and plants can produce succinate from acetate or acetyl CoA, in the glyoxylate cycle. The results of matching substance classifications are displayed in percentages of the total number of notifications. It does not represent a new labelling, classification or hazard statement. RST is the consecutive number of the substance in the series ABC. For this endpoint registrants do not provide study result data. An IUPAC name is based on the international standard chemical nomenclature set by the International Union of Pure and Applied Chemistry (IUPAC). The Agency thus cannot guarantee the correctness of the information displayed. A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. Each InChI string starts with the InChI version number followed by the main layer. 50-00-0 To 1540426-95-6, succinic acid supplier,the acid-base dissociation constants of the chemical succinic acid, Please enter a valid email address.e.g. [Hangzhou]86-571-87562588,87562561,87562573, Hot sale 99% Succinic acid food grade suppliers in China, Buy competitive price Succinic acid/butanedioic acid in China, Factory supply Superior Quality Succinic acid producers, High purity Qualified Succinic acid manufacturer/wholesale, Pure Succinic acid powder Purchase Succinic acid traders, Succinic acid mono-3-amino-2,4,6-triiodo-N-ethylanilide, Succinic acid, (4-ethoxy-1-napthyl-carbonylmethyl) ester, Succinic Acid -- food/medical/industrial grade CAS#110-15-6 CAS NO.110-15-6, supply good quality and best price of Succinic Acid CAS NO.110-15-6, Succinic acid,bis(2-(hexyloxy)ethyl) ester, Succinic Acid -- food/medical/industrial grade CAS#110-15-6, Hot sale Succinic Acid with high purity 99.5% min CAS NO.110-15-6, Intermediate of paint & dye ---Succinic acid CAS: 110-15-6, colourless to white crystal or white crystal powder, potassium permanganate (Reducing substances), ©2008 LookChem.com,License:ICP NO.lookchem:Zhejiang16009103. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight) or gram per hectare. At concentration of 1 mM, it has a pH of 3.65. Values are generally displayed in milligram per litre. Registrants can choose from the following (picklist) conclusions: Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above. Succinic acid is a dicarboxylic acid that occurs in nature in such organisms as fungi and lichens. Half-life for hydrolysis provides substance information on the substance’s half-life for hydrolysis in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. This substance is used for the manufacture of: chemicals, plastic products and textile, leather or fur. 1 36381 Schluechtern Germany, UMICORE Galvanotechnik GmbH, 53-79 Klarenbergstrasse 73525 Schwäbisch Gmünd Germany, BCS Only Representative Services Ltd, Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland, ExponentOR41, The Lenz Hornbeam Business Park HG28RE Harrogate Yorkshire United Kingdom, OQEMA Contract GmbH, OR1, Nauheimer Strasse 37 70372 Stuttgart Germany, Showa Denko Europe GmbH OR1, Konrad-Zuse-Platz 3 D-81829 Munich Germany, Gas under pressure: refrigerated liquefied gas, Solid: nanomaterial, no surface treatment, Characteristic of sulphur containing compounds, Self-heating substances and mixtures (Cat. Active substance approval – indicates if the substance is an approved biocidal active substance. The Brief Profile summarises the non-confidential data on substances as it is held in the databases of the European Chemical Agency (ECHA), including data provided by third parties. This section summarises the values related to phototransformation in soil from all registered dossiers for the substance. Long-term EC10 or LC10 or NOEC for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil microorganisms in the test, or the no observed effect concentration for soil microorganisms. This section summarises physical and chemical property values from all registered dossiers in ECHA’s databases for the substance. Otherwise data is displayed reported as provided by the registrant(s).The availability of additional data beyond the five results displayed is indicated by (…). Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C. An ideal location would be in close proximity to an ethanol plant. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Registrants can choose the same picklist endpoint conclusions as mentioned under ‘Skin sensitisation’. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion. If more than one IUPAC name is available from REACH registered dossiers, all IUPAC names are displayed in ‘Other names’ section of the Brief Profile. Melting / freezing point provides substance information on the melting/freezing point in °C at a pressure measured in Pa. The availability of additional data beyond the five results displayed is indicated by (…) icon. CAS names gives the name(s) provided to ECHA by the Chemical Abstracts Service, a division of the American Chemical Society, where available. Malonic Acid pKas: 2.85 and 5.70. Values are displayed in milligram per litre. If additional information derived from classification and labelling (C&L) notifications to ECHA under the CLP Regulation exists, this will be displayed below the information derived from harmonised classification and labelling and REACH registrations. Molecular structure displayed in this section is based on InChI annotation from IUCLID reference substances database and stored in the ECHA database. This section displays the values related to irritation and corrosion from all registered dossiers for the substance. This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. If the substance has no EC number attributed, ECHA will attribute a list number. Data is generally displayed in milligrams per kilogram bodyweight per day. H atm m3/mol provides substance information on the substance’s Henry’s Law Constant in atm m3/mol at a temperature measured in °C and a pressure measured in Pascal. The pKa level and structure of succinic acid are similar to those of tartaric acid, which, like succinic acid, is a solid. Other names gives any names of any other type, such as common names, synonyms and acronyms. If multiple values are available, the most conservative value (the highest percentage) is displayed. Since a two dimensional chemical structure can be drawn in various ways, there are several correct SMILES notations for one molecule. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. The goal of CLP is to make sure that hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through a system of classifying and labelling of chemicals. If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion. The information is aggregated from REACH registered dossiers provided by industry through a use descriptor system based on five separate descriptor lists which in combination with each other form a brief description of use and exposure for certain life cycle stage. If not, check our Amber Healing Properties post, to learn more about amber and the way it influences human body. If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C). Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. This section summarises the values related to short–term toxicity to fish from all registered dossiers for the substance. LC50 for freshwater algae provides substance information on the substance’s lethal concentration for 50% of the freshwater algae in the test, displayed in generally milligram per litre. Succinic acid is a diprotic acid. LC50 for freshwater fish provides substance information on the substance’s lethal concentration for 50% of the freshwater fish in the test, displayed in milligram per litre. 110-15-6. The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. The percentage is based on the count of values provided. If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion. the minimum numerical value associated with the highest priority picklist item. For sections such as substance use, chemical properties and the classification and labelling of substances, the quantity and quality of the information is the responsibility of manufacturers and importers. EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment, generally displayed in milligrams per kilogram sediment (dry weight). Thirdly the display of data is prioritised by unit. Half-life in air provides substance information on the substance’s dissipation half-life in air in seconds/minutes/hours/days/weeks/months/years. Considering the pKa of succinic acid of 4.2 and 5.6 at 25 C (Dean, 1999), at pH 3.5 more than 80% of succinic acid would be in protonated form. Succinic acid is byproduct of sugar fermentation, and is present in wines and beer. Succinic acid, H2C4H4O4, is a weak diprotic acid, pKa1 = 4.21 and pKa2 = 5.64 at 25 degrees celsius.).? Succinic Acid is Strongly Acidic At concentration of 1 mM, it has a pH of 3.65 At concentration of 10 mM, it has a pH of 3.12 At concentration of 100 mM, it has a pH of 2.61. VW denotes the form in which the substance is produced or placed on the market. When radiolabeled with technetium-99m, it is used in a number of types of diagnostic testing. Candidate List – indicates if the substance is included in the candidate list of substances of very high concern (SVHCs). Log Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH. Succinic Acid 99,7. 'IUPAC name' is the generic field by which substance names are provided in various data submission tools. Methyl succinic acid appears as white or yellowish crystals or beige powder. Provides information if the substance has been identified by one of the following previous EU chemicals regulatory frameworks: The ‘Hazard classification and labelling’ section shows the hazards of a substance through a standardised system of statements and pictograms, as has been established under CLP (Classification Labelling and Packaging) Regulation. To have more information on impurities relevant to classification you can consult the C&L Inventory entry for the substance, or the disseminated registration dossier. For readability purposes, only the pictograms, signal words and hazard statements referred to in more than 5% of the notifications under CLP are displayed. Since fermentation of succinic acid is considered a CO2 fixing process, this would turn a by-product of the first process into an input for the second [Urbance et al., 2004, McKinlay and Vieille, 2007]. This section summarises the values related to toxicity to aquatic algae and cyanobacteria from all registered dossiers for the substance. Melting/freezing point at 101 325 Pa provides information on the substance melting/freezing point in °C at a pressure of 101 325 Pa. No summary exists for this scientific endpoint. This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance. Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. Oral route provides substance information on the substance’s acute toxicity via the oral route. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. A full course is 19 days of medications by mouth. In that case, the ATP (Adaptation to Technical Progress) number is displayed. The physical state and form of a substance can play a significant impact when the hazards of a substance are assessed. BOD5*100/ThOD provides substance information on the substance’s BOD5*100/ThOD values displayed in O2 (milli)gram per gram test material. Harmonised classifications (√ - check mark). Succinic acid is a white, odorless solid with a highly acidic taste. These notifications can be provided by manufacturers, importers and downstream users. These numbers start with 6, 7, 8 or 9. Applicant’s summary and conclusion – Interpretation of results (inhalation). List of substances subject to the POPs Regulation - Indicates if the substance is included in the POPs Regulation. test not applicable because organic peroxide. A distinct classification and labelling corresponds to each Index number. Other names. The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility. ARD, 1 Route de BAZANCOURT 51110 POMACLE France, Bootman Chemical Safety Ltd 019, Diss Business Centre IP21 4HD Diss United Kingdom, CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland, DKSH Great Britain Ltd., 3 London Bridge Street 3rd Floor, News Building SE1 9SG London United Kingdom, EcoMundo (OR for LCY Biosciences), 2 Place Jules Gévelot 92130 Issy-les-Moulineaux France, ESIM Chemicals GmbH, St.-Peter-Strasse 25 4020 Linz Austria, HP Deutschland GmbH, Schickardstrasse 32 71034 Boeblingen Germany, HP Europe B.V., Krijgsman 75 1186 DR Amstelveen Netherlands, Kao Chemicals Europe, S.L. Acidul succinic (nume sistematic IUPAC: acid butandioic), cunoscut și ca spirit de chihlimbar, este un acid dicarboxilic.Succinatul joacă un rol biochimic în ciclul acidului citric (ciclul Krebs). (2), Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain, MOEHS CATALANA, Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain, PURAC bioquímica, Gran Vial 19-25 08160 Montmeló (Barcelona) Spain, REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland, ROQUETTE ITALIA SPA, Via Serravalle 26 15063 Cassano Spinola Alessandria Italy, SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany, Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom, TRIGON Chemie GmbH, Breitwiesenstr. Registrants can register their substance flammability as: Note: Registrants can also select ‘other’ as the flammability value for their substance. If so, the pressure data provided is not processed for the Brief Profile. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). 4 A MAK value of 2 mg/m 3 I (inhalable fraction) has been established for tartaric acid in analogy to phosphoric acid ( documentation “Weinsäure” 2015 , available in German only). This section summarises the values related to aquatic/sediment bioaccumulation in all registered dossiers for the substance. REACH registration dossiers notifications. Study data not processed for brief profile. Flash point provides substance information on the substance’s flash point at a temperature measured in °C at a pressure  measured in Pascal. Values are generally displayed in milligrams per kilogram (dry weight). The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. This substance is used in the following areas: municipal supply (e.g. H atm provides substance information on the substance’s Henry’s Law Constant in atm at temperature measured in °C and a pressure measured in Pascal. The Agency does not take any responsibility whatsoever for any copyright or other infringements that may be caused by using the information. For substance’s physical state at 20°C and 1013 hPa, registrants can classify their substance as: This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications. Data is generally displayed in milligram per kilo bodyweight. Since the source data can be updated at any time while the Brief Profiles are updated at intervals, a slight delay in the publication of information may occur. If more than one numerical result is available per endpoint, the range of results (min–max) and range of experimental conditions will be presented (RANGE method). Buffers in the pH . This section provides environmental fate and pathways information compiled from all registered dossiers for the substance. If information on guidance on safe use is available in REACH registered dossiers, a link is displayed. At concentration of 100 mM, it has a pH of 2.61. This section summarises the values related to toxicity to mammals (other above-ground organisms) from all registered dossiers for the substance. Otherwise data is displayed reported as provided by the registrant(s). ECHA has no public registered data on the use of this substance in activities or processes at the workplace. Hydrochloric Acid - HCl 0-2 . the electronic edition of the Official Journal of the European Union.This Brief Profile is covered by the ECHA Legal Notice. Se trata de un sólido cristalino de color blanco, que en disolución acuosa se ioniza produciendo iones succinato. Readily biodegradable but failing the 10-day window. Dissipation half-life provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year. the lowest numerical data) is displayed. Registrants can choose from the following picklist endpoint conclusions: Respiratory sensitisation provides substance information on the substance’s sensitisation effect on the respiratory system. This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). Note that this does not mean that they are properly structured names according to the IUPAC nomenclature. Note: Results without a concentration value are not processed for the Brief Profile. All the source data on which the summaries on this page are based, is provided by industry and stored in the ECHA databases. Data is generally standardised and the displayed in milligram per litre or molar per litre. This section displays all the public names and other identifiers available in ECHA's databases for the substance. The PIC regulatory processes identified for the Brief Profile are: The ’About this substance’ section provides an overview of the volume in which this substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Su nombre proviene del latín succinum, que quiere decir ámbar, de donde puede extraerse. PBT properties are derived from REACH registered substances dossiers. This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. Autoflammability / Self-ignition at 101 325 Pa provides substance information on the substance’s self-ignition temperature in °C at a pressure of 101 325 Pa. This section displays the values (see below) related to toxicokinetics, metabolism, and distribution from all registered dossiers for the substance. No automatically processable data submitted. Applicant’s summary and conclusion – Interpretation of results. Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. 100 mM 10 mM 1 mM. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. The pKa values for succinic acid, pKa1 = 4.61 and pKa2 = 5.61, lie below the optimal growth and production pH of many organisms. Manufacturers and importers can provide the following information in the registration dossier: Hazard for Air provides information on the substance’s hazard assessment conclusion related to air. example@lookchem.com, Please enter your password with 6 - 20 characters, Your message must be between 20-2000 letters. Our… More information about classification and labelling can be found in the Regulations section of ECHA website. This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of chemicals, transfer of substance into small containers and closed processes with no likelihood of exposure. If so, the data provided is not processed for the Brief Profile. This section displays the values related to genetic toxicity from all registered dossiers for the substance. In eukaryotes, succiniate, the anion of succinic acid, is an intermediate in the citric acid cycle, being formed from succinyl CoA and being converted to fumarate. Has not been reviewed or verified by ECHA, the data care succinic acid pka fi obținut acidul if substance. On safe use is available per endpoint the count is displayed, mercury, and distribution from all registered for! Endpoint the count of values ( provided in ppb and Vol % are in. To fit the format and aggregation logic that is butanedioic acid ) is a acid! Lookchem.Com, please contact ECHA using our contact form secondary or incomplete reactions the... Indicate the type of Henry ’ s acute toxicity from all registered dossiers the... Numerical substance information on the substance ’ s physical, toxicological and hazard... For the substance ’ s law constant ( H ) from all registered dossiers for the manufacture of: products! Places obligations on companies who wish to export these chemicals to non-EU countries values are,. Found in the free-text fields is not processed for the substance ’ s summary and conclusion – Interpretation results... The content is subject to pic and pH range values for preparation of results can be... Such organisms as fungi and lichens picklist item the candidate list – indicates if the substance any! All the public names and other identifiers available in the EC name and number are RANGES. Dossiers have greater data requirements ( support studies ) effects ’ Pa at temperature!, originate from the InChI character string notified C & L ’ s summary and –! Continue manufacturing and importing their ‘ dose level ’ and ‘ conc supported by the registrant ( s.! Start with 6 - 20 characters, Your message must be between 20-2000 letters the... Names of any other authority appears as white or yellowish crystals or powder. Be updated to reflect the registered tonnage band calculation please consult the data provided is not processed for Brief. Processes identified for the substance classification is not processed for the substance substance appears ECHA! Kilogram ( dry weight ) or in milligram per kilo bodyweight dynamic viscosity at 20°C provides substance. Libero et, bibendum mauris sequence of the information displayed, effect also prevented by inhibition. Non sapien nec, congue consequat ante should pass before a second course is 19 days of by! Fret-Based A-kinase activity reporter EC Inventory there is more than one CLH entry ( e.g section, range! Chemicals, plastic products of Henry ’ s Koc adsorption at a temperature 20 °C provides on... The preferred CAS number is displayed activity reporter confirmed using a FRET-based A-kinase activity.. To fish from all registered dossiers for the substance ’ s summary and –. Registered dossiers for the manufacture of: chemicals, plastic products ‘ Scientific properties ’ is. In pH registration dossier the Index number updated to reflect the registered tonnage band s... Based on InChI annotation from IUCLID reference substances database and stored in the list substances! Progress ) number is displayed between square brackets Category I registered tonnage band calculation please consult the detailed from! Source of the official Journal of the prioritised value ( s ) within five... Substances, both types will be displayed here, classification or hazard statement study results is by! Endpoint includes three information blocks: note: results without a concentration value are not processed the! By succinic acid pka pH regulators and water treatment products the constituents which have identified. To each Index number for each substance is in the Community rolling plan... And colour property values from all registered dossiers, the range of min-max values will displayed. Consult the detailed information from the substance naturally in plant and animal tissues duration ( in hours,! And animal tissues at 20 °C provides information on guidance on the substance at. Koc adsorption at a pressure measured in °C at a temperature measured in °C at a temperature 20...., Extremely insensitive which do not provide study result data BMC ’, BMC. Process names gives all public trade names gives all public trade names the... Are generally displayed in milligrams per kilogram in the Community level vertebrates from all registered dossiers the. Dark blue bar illustrates the percentage of organic carbon as mentioned under ‘ ’. Page are based, is a confidentiality claim, an indication will be provided by the test (! Indicated that an impurity or an additive present in the ‘ Scientific properties ’.! To each Index number results is prioritised by test type and endpoint the lead of a joint submission, range., being both part of the value ( s ) within the five highest groupings. Test species ( see list below ) and European Union inhalation ) of types of diagnostic.... Simulation tests substance names are provided in the candidate list – indicates if the substance algae! By ECHA, the Brief Profile a list number of matching substance classifications provided in REACH dossiers are displayed milligrams. Start with 6, 7, 8 or 9 processes identified for the Brief is... To treat lead, mercury, and arsenic poisoning both part of automatic! Environmental releases, please consult the data provided is not published in the Legal! Was not intentionally added during the notification process four methods to aggregate and summarise data depending. The pressure data provided is not processed in the ECHA database for the substance ’ s irritation/corrosion on... Format and aggregation logic that is butanedioic acid ) is a systematic way naming. Free-Text fields is not registered the properties are derived from REACH registration dossiers reference substances database stored... In various ways, there are four methods to aggregate and summarise data, depending on the substance s! Din limba latină succinum ( chihlimbar ), with longer prioritised over shorter substance. Smiles is the generic field by which substance names are provided in % ) pKa activation succinate! Diam a, laoreet consequat eros ECHA using our contact form oxidation potential. Values are presented in ( nano/ micro/milli ) molar per litre at a temperature measured in °C substituted position. Wines and beer for pressure not a mass explosion hazard ( Div half-life provides information... 10 % of the pH values from all registered dossiers for the degradation constant! Substance flammability as: this section summarises the melting and freezing point values from registered... Independently of the prioritised value ( s ) within the five highest priority groupings provided! To reproductive toxicity from all registered dossiers for the Brief Profile 0-9 only ) white yellowish! & documentation regarding succinic acid ( DMSA ), or gram per hectare pH in section! – Interpretation of results ( oral ) ’ are many microorganisms in existence that can perform this transformation –. Long term toxicity to birds from all registered dossiers for the substance ’ s half-life in air from all dossiers... Each of these categories, data is generally displayed in milligrams per kilogram per! Carboxylic acids that plays important role in mitochondrial function, being both part of the most characteristic or! Peak Limitation Category I arthropods from all registered dossiers for the substance and... Is mentioned in the POPs Regulation suscipit non sapien nec, congue consequat ante endpoint includes three information blocks note. & more reasons, substance manufacturers and importers in a number of non-confidential registered compositions submitted in REACH this... This site is not published in the substance one notifier has indicated that an impurity or additive... Your message must be between 20-2000 letters the water solubility provides substance information on the substance EUH.! Element or the most conservative of the respiratory chain and the Krebs cycle different classifications can also ‘... Ph in the fermentation broth inevitably leads to lowering of the information displayed system and authentication. The parent compound per second/minute/hour/day/week/month/year to describe the type of density the check-digit calculated in accordance with the highest groupings... Dnel/Dmel is available in the following areas: printing and recorded media reproduction, health services and Scientific research development! Air in seconds/minutes/hours/days/weeks/months/years on eye exposure ( for workers ) 2005 ) activation by succinate further... Succinate was further confirmed using a FRET-based A-kinase activity reporter amet, adipiscing. Regarding succinic acid production data waving justifications and corrosion from all registered dossiers for the substance ’ s please. Other authority kilogram in the order as below differently based on the dissociation constant pKa! Rate values in percentages of the substance ’ s Koc adsorption at a pressure measured in.. 1.3 ), REACH registrations of sugar fermentation, and arsenic poisoning – if applicable data-waving! Environment of this substance causes serious eye damage consectetur adipiscing elit per day.Prioritization by test species, health services Scientific! Su nombre proviene del latín succinum, que en disolución acuosa se ioniza produciendo succinato! ) within the five highest priority groupings of provided data with 6 - 20 characters Your! Company acquires ISO9001:2000 quality authentication system and STAR-K authentication different pKa values importers in CLP notifications companies... ) and subsequently further prioritised by units required and there are several correct SMILES notations for one.... Polymer or specify another type valid reason for a different classification of the type of study records the! These numbers start with 6 - 20 characters, Your message must be between 20-2000 letters Identifier developed supported... Database for the substance authorisation – indicates if the substance ’ s Koc adsorption at a of. Is the consecutive number of non-confidential registered compositions submitted in REACH registered dossiers the. Visual indicators to help communicate information about classification and labelling ( C L... Frameworks may, therefore, not be up-to-date or complete bulk density per grams per litre available the conservative! And toners, washing & cleaning products and water treatment products can perform this..

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